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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNM1L
All Species:
46.67
Human Site:
S126
Identified Species:
73.33
UniProt:
O00429
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00429
NP_005681.2
736
81877
S126
S
G
N
N
K
G
V
S
P
E
P
I
H
L
K
Chimpanzee
Pan troglodytes
XP_520720
896
98575
S286
S
G
N
N
K
G
V
S
P
E
P
I
H
L
K
Rhesus Macaque
Macaca mulatta
XP_001086126
725
80517
S126
S
G
N
N
K
G
V
S
P
E
P
I
H
L
K
Dog
Lupus familis
XP_864886
736
81869
S126
S
G
N
N
K
G
V
S
P
E
P
I
H
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1M6
742
82640
S132
S
G
N
N
K
G
V
S
P
E
P
I
H
L
K
Rat
Rattus norvegicus
O35303
755
83890
S139
S
G
N
N
K
G
V
S
P
E
P
I
H
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001073190
696
77727
S126
S
G
N
N
K
G
I
S
P
E
P
I
H
L
K
Frog
Xenopus laevis
NP_001080183
698
77807
S126
S
G
N
N
K
G
I
S
S
E
P
I
H
L
K
Zebra Danio
Brachydanio rerio
Q7SXN5
691
77244
S125
S
G
N
N
K
G
I
S
D
E
P
I
H
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P27619
877
97791
R118
S
N
I
P
I
N
L
R
V
Y
S
P
H
V
L
Honey Bee
Apis mellifera
XP_394947
721
81070
C126
A
G
S
N
K
G
I
C
P
E
P
I
N
L
K
Nematode Worm
Caenorhab. elegans
P39055
830
93389
S118
T
G
Q
N
K
G
I
S
P
H
P
I
N
L
R
Sea Urchin
Strong. purpuratus
XP_802061
717
80361
V126
A
G
T
N
K
G
I
V
H
D
A
I
H
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LFT2
780
86625
S137
S
G
E
N
K
G
V
S
D
I
P
I
G
L
K
Baker's Yeast
Sacchar. cerevisiae
P54861
757
84953
S155
A
G
K
D
K
G
I
S
K
I
P
I
N
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.5
98.5
99.1
N.A.
97.8
96.4
N.A.
N.A.
89.8
87
86
N.A.
33.9
66.8
35.6
68.7
Protein Similarity:
100
79.9
98.5
99.5
N.A.
98.3
97.2
N.A.
N.A.
91.8
90.9
90.3
N.A.
52.2
79.7
53.9
82.2
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
86.6
86.6
N.A.
13.3
66.6
60
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
93.3
93.3
N.A.
26.6
93.3
86.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.4
45.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.4
65.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
73.3
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
0
0
0
14
7
0
0
0
0
0
% D
% Glu:
0
0
7
0
0
0
0
0
0
67
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
94
0
0
0
94
0
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
7
0
0
74
0
0
% H
% Ile:
0
0
7
0
7
0
47
0
0
14
0
94
0
0
0
% I
% Lys:
0
0
7
0
94
0
0
0
7
0
0
0
0
0
80
% K
% Leu:
0
0
0
0
0
0
7
0
0
0
0
0
0
94
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
60
87
0
7
0
0
0
0
0
0
20
0
0
% N
% Pro:
0
0
0
7
0
0
0
0
60
0
87
7
0
0
0
% P
% Gln:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
14
% R
% Ser:
74
0
7
0
0
0
0
80
7
0
7
0
0
0
0
% S
% Thr:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
47
7
7
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _